Example sentences for: adducts

How can you use “adducts” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • first reported oxidative stress caused by t-butylhydroperoxide or iron/ascorbate could lead to 4-HNE protein adducts in hepatocytes [ 62 ] . Further studies by these researchers attempted to identify the common epitope recognized by the 4-HNE antibodies.

  • Cisplatin causes two types of DNA damage, DNA adducts and inter-stranded cross-linking, resulting in activation of apoptosis pathway in the target tumor cells [ 13 14 ] . Our results suggest that inhibition of tyrosine kinase activity of the potential targets by Gleevec appear to potentiate the effect of cisplatin in DNA-damage induced apoptosis in A549 cells.

  • In light of the previous publication on the role of 8-OH-dG adducts in a rat model of type 2 diabetes [ 31 ] , and the finding that the Ogg1 gene was over-expressed in human type 2 diabetes, we evaluated the expression of Ogg1 protein in pancreas specimens from type 2 diabetic and healthy subjects, as a marker for β-cell oxidative DNA damage in type 2 diabetes.

  • ERK activation and 4-HNE protein adducts formation as a result of oxidative stress

  • Such an apoptotic defect could account for the increasing intensity of Ogg1 staining, following accumulated levels of 8-OH-dG adducts with longer duration of diabetes.


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