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Example sentences for: additionally
How can you use “additionally” in a sentence? Here are some example sentences to help you improve your vocabulary:
The majority of the patients died with the first two months of TB treatment and we did not conduct autopsies, additionally the majority of the patients in the study were sputum culture negative at 2 months of treatment.
Additionally, we investigated whether the Pseudomonas homolog of LcrG, PcrG, could transcomplement an lcrG strain of Y. pestis . The opportunistic pathogen Pseudomonas aeruginosa utilizes a type III secretion system for intracellular delivery of toxins [ 21 22 23 ] that is the most similar to the Yersinia system [ 21 ] . Several components of the Pseudomonas system have been demonstrated to functionally complement genetic defects in the Yersinia homologs including the LcrV homolog, PcrV [ 24 25 ] . Homologs of LcrG and LcrV (i.e.
4) [ 34 ] . Furthermore, the Borrelia plasmids that encode ERF, also almost always additionally encode a λ-type exonuclease, even if it is not the adjacent gene.
Organic phosphate compounds are the central metabolites of all biological systems [ 1 2 ] . Some are the basic building blocks of nucleic acids, some like ATP and GTP, are additionally, cellular energy stores, others like cAMP or cGMP are messengers in signal transduction, and, yet others, such as FAD, NAD, thiamine phosphates and pyridoxal phosphate are cofactors for a range of enzymes [ 1 2 ] . Protein domains belonging to a relatively small set of structural folds are known to bind or catalyze reactions that utilize these organic phosphate compounds (see SCOP database: http://scop.mrc-lmb.cam.ac.uk/scop/) [ 3 4 ] . Several of these folds trace back to some of the earliest phases of the evolution of the protein world, and participate in a wide range of disparate biological functions in extant proteins [ 4 5 ] . Some folds, such as the P-loop fold, the Rossmann fold and the Hsp70-like fold, have been well studied, and comprise mainly of dedicated nucleotide binding or hydrolyzing proteins [ 6 7 8 9 ] . Others, such as the palm-domain, which is found in adenylyl cyclases and various nucleic acid polymerases, belong to more generalized protein folds that contain representatives with diverse biochemical activities [ 4 10 11 ] . Current availability of extensive genome sequence data, allows one to identify less numerous, nevertheless biological important organic phosphate-binding domains that may have previous eluded detection.
Additionally, the model is an unbiased estimator: the slopes are 1, and the intercepts are 0. The results are similar for the intercepts, and for amino-acid usages (Table 4).
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