Words similar to acetazolamide

Example sentences for: acetazolamide

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The hyperemic cerebrovascular response to hypercapnia or acetazolamide is not inhibited by nitric oxide synthase inhibitors such as N G-monomethyl-L-arginine (L-NMMA) suggesting that NO does not mediate vasoreactivity [ 23 24 ] . The mechanism of acetazolamide vasodilation, beyond smooth muscle intracellular and extracellular acidosis due carbonic anhydrase inhibition, is unclear.
Reduced ΔCBF res would be expected when the resistive component is increased reducing the amplitude of the acetazolamide induced plateau response.
2 O and PET, a further study of rCBF following 1 g of acetazolamide demonstrated the peak response to occur at 10 minutes while the plateau phase occurred during the twenty to thirty minute time period post acetazolamide [ 22 ] . The measurements in the current study obtained at twenty and thirty minutes post acetazolamide injection therefore, probably corresponds to the plateau phase of reported acetazolamide responses.
The vasodilator effect of acetazolamide on the cerebral vasculature has been characterized by both PET and transcranial Doppler (TCD) studies [ 21 22 ] . At a dose of 15 mg/kg the effect of acetazolamide is thought to be supramaximal with maximal cerebral vasodilation induced within about 20 minutes.
Acetazolamide Challenge Studies - global CBF (Table 2)