Words similar to acetazolamide
Example sentences for: acetazolamide
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The hyperemic cerebrovascular response to hypercapnia or acetazolamide is not inhibited by nitric oxide synthase inhibitors such as N G-monomethyl-L-arginine (L-NMMA) suggesting that NO does not mediate vasoreactivity [ 23 24 ] . The mechanism of acetazolamide vasodilation, beyond smooth muscle intracellular and extracellular acidosis due carbonic anhydrase inhibition, is unclear.
2 O and PET, a further study of rCBF following 1 g of acetazolamide demonstrated the peak response to occur at 10 minutes while the plateau phase occurred during the twenty to thirty minute time period post acetazolamide [ 22 ] . The measurements in the current study obtained at twenty and thirty minutes post acetazolamide injection therefore, probably corresponds to the plateau phase of reported acetazolamide responses.
In this way, the attributable treatment effects were compared for the analysis of the visual activation and acetazolamide responses on a patient-by-patient basis.
The CBF response curve to acetazolamide can be considered like a high pass filter with an onset time constant to a steady state τ 1 and an offset time constant of τ 2 . Alteration and prolongation of τ 2 will correspond to prolonged cerebral vascular response time . An important concept of a high pass filter is that the system response is dependent on both the resistive (R) and capacitative (C) elements.
Acetazolamide Challenge Studies - global CBF (Table 2)