Example sentences for: ac

How can you use “ac” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Snonymous coding sequence polymorphisms 111046 C→T and 115744 C→T and intronic single-nucleotide polymorphism (SNP) 107724 A→T were identified (all 329D1 sequence coordinates refer to positions on GenBank AC008438.

  • AC = Average Unit Cost d = Subscript that indicates delivery component of a cost or volume DC = Total Delivery Cost Ev = Long-run variability of non-delivery institutional (fixed) costs.

  • Organic phosphate compounds are the central metabolites of all biological systems [ 1 2 ] . Some are the basic building blocks of nucleic acids, some like ATP and GTP, are additionally, cellular energy stores, others like cAMP or cGMP are messengers in signal transduction, and, yet others, such as FAD, NAD, thiamine phosphates and pyridoxal phosphate are cofactors for a range of enzymes [ 1 2 ] . Protein domains belonging to a relatively small set of structural folds are known to bind or catalyze reactions that utilize these organic phosphate compounds (see SCOP database: http://scop.mrc-lmb.cam.ac.uk/scop/) [ 3 4 ] . Several of these folds trace back to some of the earliest phases of the evolution of the protein world, and participate in a wide range of disparate biological functions in extant proteins [ 4 5 ] . Some folds, such as the P-loop fold, the Rossmann fold and the Hsp70-like fold, have been well studied, and comprise mainly of dedicated nucleotide binding or hydrolyzing proteins [ 6 7 8 9 ] . Others, such as the palm-domain, which is found in adenylyl cyclases and various nucleic acid polymerases, belong to more generalized protein folds that contain representatives with diverse biochemical activities [ 4 10 11 ] . Current availability of extensive genome sequence data, allows one to identify less numerous, nevertheless biological important organic phosphate-binding domains that may have previous eluded detection.

  • Previously known, conserved domains were identified using PSI-BLAST derived profiles for them, with the RPS-BLAST program [ 45 ] . Sequence-structure threading was performed using the 3DPSSM server http://www.sbg.bio.ic.ac.uk/~3dpssm/.

  • The first two exons of the GPC5 gene are present in BAC clone accession number AL138714, exons 3,4,5 in AC027429, exon 6 in AL162456, exon 7 in AL163537 and exon 8 in AL157363 (Table 2).


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