Words similar to aa
Example sentences for: aa
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An open reading frame (ORF-F) identified as a necessary part of the Pseudomonas stutzeri pdt locus coding for the synthesis pathway of pdtc (Figure 1) was found to have 57% identity to M. tuberculosis MoeZ at the amino acid (AA) level.
As expected, fractions were also observed that exhibited no APN enzymatic activity but bound Cry1Aa on slot blots (Fig.
Due to the increased molecular weight of the EGFP-tagged cPLA 2 , the two forms of cPLA 2 did not separate as well, making the gel shift more difficult to visualize, but generally mirrored the gel shift characteristics of the endogenous cPLA 2 . These results suggest that, in response to MEK1 inhibition, there is a quantitative, dose-dependent decrease in AA release that correlates well with the loss of ERK activation, but not with the extent of cPLA 2 Ser 505phosphorylation.
In addition, using cells expressing wild-type cPLA 2 and cPLA 2 with S505A or S727A mutations, it was found that translocation kinetics and membrane targeting in response to ATP or ionomycin was similar to wild-type cPLA 2 . These data suggest that MEK1 inhibition reduces cPLA 2 catalytic activity and AA release independently of phosphorylation and translocation.
Binding studies indicated that the affinity of the cadherin for Cry1Aa is equivalent to that of the brush border membrane vesicles from B. mori [ 16 ] , an affinity that is substantially lower than the APN affinities reported.