Words similar to aa-tttt-

Example sentences for: aa-tttt-

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Since the L1 EN consensus site is 3'-AA-TTTT-5', the first cut would expose a T-rich sequence on the target sequence from which an A-rich template could be primed for reverse transcription.
It is believed that the tendency of EN to nick target DNA at the consensus 3'-AA-TTTT-5' exposes a T-rich sequence, to which the poly(A) tail of an L1 transcripts can anneal thereby priming reverse transcription [ 16 19 20 21 ] . A new L1 insertion is usually flanked by short direct repeats derived from the target DNA locus upon L1 integration [ 22 23 ] ; these repeats are referred to as target-site duplications (TSDs).