Example sentences for: az

How can you use “az” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Since SNIP1 is a nuclear protein, the interaction between SNIP1 and Az may require the nuclear translocation of Az.

  • The Activation of the BMP type I receptor induces Smad1-dependent nuclear translocation of both HsN3 and Az

  • Smad1 is translocated from the cytoplasm to the nucleus upon its activation by the BMP type I receptors [ 40 ] . The physical interaction between Smad1, Az and HsN3 suggests that BMP signaling might regulate the intracellular localization of Az and HsN3.

  • Since we again only detected the pro-sequence form of HsN3 in Az precipitates, such a ternary complex is likely formed along the assembly pathways of HsN3.

  • The 26S proteasome is responsible for the bulk turnover of cytoplasmic and nuclear proteins in eukaryotic cells and also plays a key role in the regulation of cell cycle, signal transduction, transcription as well as antigen presentation [ 17 18 19 20 21 ] . Most of the known proteasomal substrates are marked and targeted to proteasome by ubiquitination [ 17 19 20 ] . Ubiquitination, however, is not an obligatory step for substrate targeting to proteasome [ 17 18 20 ] . The degradation of the ornithine decarboxylase (ODC), the rate-limiting enzyme for polyamine synthesis, involves a protein named antizyme (Az), which binds and targets ODC to 26S proteasome for degradation [ 18 ] . However, ODC has remained an "orphan" in Az-dependent proteasomal degradation.


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