Example sentences for: aza-

How can you use “aza-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Of the six cell lines with RARB gene methylated, three (HT-3, MS751, and ME-180) exhibited reactivation upon treatment with 5-Aza-2' deoxycytidine or n-butyrate alone or the combination of the two.

  • The MGMT gene exhibited promoter hypermethylation in four of the cell lines, which upon treatment with 5-Aza-2' deoxycytidine showed reactivation of expression in three (2102E-R, 833K-E, and Tera-2).

  • We found that 5-Aza-2'-deoxycytidine treatment alone or in combination with n-butyrate resulted in reactivation of gene expression in most cell lines that showed promoter methylation.

  • Transcriptional silencing of genes resulting from DNA hypermethylation of CpG islands is reversed by treatment with the hypo-methylating agent 5-aza-2'-deoxycytidine and HDAC-inhibiting agent n-butyrate in a dose and duration-dependent manner.

  • Transcriptional silencing of genes resulting from DNA hypermethylation of CpG islands is reversed by treatment of the hypo-methylating agent 5-aza-2'-deoxycytidine in a dose and duration-dependent manner.


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