Words similar to aza-
Example sentences for: aza-
How can you use “aza-” in a sentence? Here are some example sentences to help you improve your vocabulary:
To further examine the role of promoter methylation in gene inactivation, we treated five NSGCT cell lines (2102E-R, 833K-E, Tera-1, Tera-2, and 218A) with 5-Aza-2' deoxycytidine and analyzed the expression of MGMT , RASSF1A , RARB , and BRCA1 genes.
Both methylated cell lines (HT-3 and SiHa) and three (C-33A, MS751, and ME-180) of the four unmethylated cell lines showed reactivation upon exposure to 5-Aza-2' deoxycytidine or in combination with n-butyrate.
The SW756 cell line with methylation and one of the two unmethylated cell lines showed reactivated expression upon treatment with 5-Aza-2' deoxycytidine or in combination with n-butyrate, but not with n-butyrate alone.
5-Aza-2' deoxycytidine and n-butyrate treatment, and analysis of gene expression
Transcriptional silencing of genes resulting from DNA hypermethylation of CpG islands is reversed by treatment with the hypo-methylating agent 5-aza-2'-deoxycytidine and HDAC-inhibiting agent n-butyrate in a dose and duration-dependent manner.
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