Example sentences for: β-catenin

How can you use “β-catenin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This approach is not readily applicable to the Wnt response because the critical step in signal transduction is the block in β-catenin phosphorylation and degradation, leading to the accumulation of newly-synthesized β-catenin.

  • Nuclear β-catenin was also absent from the ventricular zone cells in P0 transgenic animals.

  • No nuclear staining was seen in these structures in most non-transgenic animals, suggesting that weak activation of Wnt signaling may occur with overexpression of wild type β-catenin protein.

  • Human β-catenin exon 3 was PCR-amplified from transgenic mouse DNA and sequenced to verify presence or absence of the codon 37 mutations.

  • The secreted glycoproteins in the Wnt/Wingless (Wg) family serve diverse functions in developmental processes, ranging from cell fate specification and cell proliferation to cell migration and cell polarity [ 1 2 ] , and deregulation of the Wnt signaling pathway can lead to cancer [ 3 4 ] . In a simplified model of the canonical Wnt/β-catenin signaling pathway, the binding of Wnts to their receptors activates a downstream component, Dishevelled (Dsh).


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