Example sentences for: β-box

How can you use “β-box” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 6Ashows, a synthetic β-box peptide competed for binding to N-CoR, albeit somewhat less efficiently than native GRIP1 NR box 2. Similar results were obtained in competition experiments that used GST-GRIP1 instead of GST-N-CoR (data not shown).

  • Next, we examined whether the β-box would bind other NRs.

  • The hormone-dependent component of the ERβ /N-CoR interaction maps to the extreme C-terminus of N-CoR, which has not been previously implicated in NR interactions, and requires a sequence that resembles an ERβ-specific NR box (PLTIRMLS, β-box).

  • Intriguingly, human SMRT contains a sequence insertion at the position of the hydrophobic pair in the N-CoR β-box, which apparently leads to deletion of both residues (N-CoR/RMLS>SMRT/RLqagvmaS) [ 52 ] . Perhaps SMRT contains a different NR interacting motif or the N-CoR NR box sequence may be more complex than we have initially reported here.

  • What features of the β-box contribute to ERβ specificity?


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