Example sentences for: β-cells

How can you use “β-cells” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In this regard, the present findings support the idea derived from previous findings on mouse [ 15 ] or obese-hyperglycaemic mouse β-cells [ 16 ] . However, PMA-induced PKC-independent hyperpolarization of β-cells was not previously reported [ 15 16 ] . The reason for the discrepancy is not clear at the moment.

  • However, the nuclear localization of 8-OH-dG [ 32 ] and the increased Ogg1 reported here are consistent with a model in which mitochondrial Ogg1 is up-regulated but nuclear Ogg1 is not, leading to an increase in nuclear but not mitochondrial 8-OH-dG adducts [ 32 ] . Further studies will be required to resolve this issue, but β-cells in type 2 diabetes may well suffer from both nuclear and mitochondrial DNA damage, leading to decreased β-cell function and eventual loss of β-cell mass.

  • In the presence of 5.5 mM glucose, 63% of tested β-cells (5/8) showed spontaneous action potentials superimposed on a slow depolarizing potential, and PMA (80 nM) inhibited these action potentials as well (Fig.

  • Therefore, BIM can be used as a PKC inhibitor in rat pancreatic β-cells, as already shown in other tissues including murine macrophages [ 26 ] , rat adrenal cortex [ 27 ] , human melanocytes [ 28 ] and rabbit vetricular myocytes [ 20 ] .

  • Insulin-like growth factor-1 may promote insulin secretion and prevent apoptosis of β-cells in vivo [36], and addition of this factor at stage 4 reduced apoptosis approximately 10-fold (see Figure 1A; data not shown).


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