Example sentences for: β-cell

How can you use “β-cell” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For instance, addition of glucagon-like peptide-1, TGF-β ligands, or other factors that potentiate β-cell maturation, growth, and insulin secretion [46,47,48] may improve the methods described here.

  • ngn3, Pdx1, and Hb9 are essential factors for mammalian β-cell development [22], and their expression in stage 3 suggested the potential for deriving IPCs.

  • βOgg1 is an alternatively spliced form of Ogg1 that contains a mitochondrial targeting signal in the C-terminal portion of the protein [ 41 ] . Specific upregulation of mitochondrial but not nuclear Ogg1 occurs during aging in rodents [ 42 ] . A specific increase of Ogg1 in islet cell mitochondria is consistent with the idea that increased β-cell mitochondrial oxidative metabolism due to hyperglycemia is a major factor behind the DNA damage.

  • We hypothesized that oxidative DNA damage plays a role in the β-cell dysfunction and loss that occurs in human type 2 diabetes.

  • These results provide a novel insight of modulation mechanism of insulin secretion by PMA, increases insulin secretion by activation of PKC, and meanwhile decrease insulin secretion by impairing β-cell excitability in a PKC-independent manner in rat pancreatic β-cells.


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