Example sentences for: ypop

How can you use “ypop” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To confirm these data and gain some hints for the existence of a CCR4-NOT complex in mammals, we investigated whether the interaction between yCCR4 and yPOP2 in the CCR4-NOT complex is conserved for the human ortholog, hCCR4.

  • Firstly, we identified yCCR4 mammalian orthologs and demonstrated that the human member can interact with the human yPOP2 homologs.

  • Consistently, the region encompassing the LRR and part of the C-terminus (residues 302-668) has been defined as the smallest region necessary and sufficient for the association of yCCR4 with yPOP2 [ 11 ] .

  • Here we report the identification of nineteen yCCR4-like proteins in eukaryotes and show, by phylogenetic and genomic analyses, that they are grouped into four distinct families, one of which contains the yCCR4 orthologs : these orthologs, in animals, have conserved the yCCR4 leucine-rich repeat, and we show, using two-hybrid assays and far-Western experiments, that the human protein binds to the human yPOP2 homologs, i.e. hCAF1 and hPOP2, in a LRR-dependent manner.

  • Likewise, mCAF1, which has lost the N-terminal transactivation domain of yPOP2, binds to yCCR4 with a higher affinity than yPOP2 [ 11 ] .


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