Example sentences for: ypop

How can you use “ypop” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Here we report the identification of nineteen yCCR4-like proteins in eukaryotes and show, by phylogenetic and genomic analyses, that they are grouped into four distinct families, one of which contains the yCCR4 orthologs : these orthologs, in animals, have conserved the yCCR4 leucine-rich repeat, and we show, using two-hybrid assays and far-Western experiments, that the human protein binds to the human yPOP2 homologs, i.e. hCAF1 and hPOP2, in a LRR-dependent manner.

  • To determine whether yCCR4-yPOP2 interactions are evolutionarily conserved, we examined whether hCCR4 can bind hCAF1 and hPOP2 in a two-hybrid assay in mammalian cells.

  • In yeast, yCCR4 is one of the components of the 1.0 MDa CCR4-NOT complex, which also includes yPOP2 and at least five yNOT proteins.

  • Interestingly, we found that hCCR4 also binds to the second human yPOP2 paralog, hCAF1.

  • Likewise, mCAF1, which has lost the N-terminal transactivation domain of yPOP2, binds to yCCR4 with a higher affinity than yPOP2 [ 11 ] .


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