Example sentences for: ypop

How can you use “ypop” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Consistently, the region encompassing the LRR and part of the C-terminus (residues 302-668) has been defined as the smallest region necessary and sufficient for the association of yCCR4 with yPOP2 [ 11 ] .

  • Firstly, we identified yCCR4 mammalian orthologs and demonstrated that the human member can interact with the human yPOP2 homologs.

  • To determine whether yCCR4-yPOP2 interactions are evolutionarily conserved, we examined whether hCCR4 can bind hCAF1 and hPOP2 in a two-hybrid assay in mammalian cells.

  • Several components of the yCCR4-associated complexes have already been identified in humans: two homologs of yPOP2 (named hCAF1 and hPOP2/hCALIF) [ 16 17 18 19 ] , and homologs of NOT proteins (named hNOT1, hNOT2, hNOT3, hNOT4) [ 19 ] . Moreover, interactions between these proteins were demonstrated [ 19 20 ] . Yet, at the present time there has been no report of a human protein that would be structurally and functionally close to yCCR4.

  • Since the presently characterized mammalian yCCR4 ortholog has conserved the ability to bind yPOP2 homologs and displays high sequence similarities with yCCR4 in the nuclease core domain, it suggests that the mammalian yCCR4 orthologs might also be associated with a deadenylase function.


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