Example sentences for: ypop
How can you use “ypop” in a sentence? Here are some example sentences to help you improve your vocabulary:
Here we report the identification of nineteen yCCR4-like proteins in eukaryotes and show, by phylogenetic and genomic analyses, that they are grouped into four distinct families, one of which contains the yCCR4 orthologs : these orthologs, in animals, have conserved the yCCR4 leucine-rich repeat, and we show, using two-hybrid assays and far-Western experiments, that the human protein binds to the human yPOP2 homologs, i.e. hCAF1 and hPOP2, in a LRR-dependent manner.
To determine whether yCCR4-yPOP2 interactions are evolutionarily conserved, we examined whether hCCR4 can bind hCAF1 and hPOP2 in a two-hybrid assay in mammalian cells.
In yeast, yCCR4 is one of the components of the 1.0 MDa CCR4-NOT complex, which also includes yPOP2 and at least five yNOT proteins.
Interestingly, we found that hCCR4 also binds to the second human yPOP2 paralog, hCAF1.
Likewise, mCAF1, which has lost the N-terminal transactivation domain of yPOP2, binds to yCCR4 with a higher affinity than yPOP2 [ 11 ] .
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