Words similar to yccr

Example sentences for: yccr

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Hence, according to the present data, proteins of the angel, 3635 or nocturnin families may deserve the same putative function as yCCR4, i.e. deadenylation, or at least share common substrate binding and/or catalytic specificities (for instance preference for RNA and/or poly (A) tail).
Along this line, BLAST searches in bacteria databases disclosed, in one incompletely sequenced bacterial genome ( Paenibacillus azotofixans ), an open reading frame (nt 3822 to 4583 in the AJ299453 genomic clone) which contains almost all and displays significant similarity with the yCCR4 C-terminal region, but does not contain a LRR nor a N-terminal domain.
The search for yCCR4-related proteins identifies possible orthologs of yCCR4, according to the sequence analyses reported above.
Since the presently characterized mammalian yCCR4 ortholog has conserved the ability to bind yPOP2 homologs and displays high sequence similarities with yCCR4 in the nuclease core domain, it suggests that the mammalian yCCR4 orthologs might also be associated with a deadenylase function.
Likewise, mCAF1, which has lost the N-terminal transactivation domain of yPOP2, binds to yCCR4 with a higher affinity than yPOP2 [ 11 ] .