Words similar to yccr

Example sentences for: yccr

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Whether such a LRR-containing gene could be the common ancestor for all the yCCR4-related genes (with deletion of the LRR and several duplication events for the angel, 3635 and nocturnin families) is not known.
In the course of our search for genes encoding proteins displaying significant similarity with the yeast yCCR4 factor, the best hits were found for cDNAs encoding a family of proteins from C. elegans, D. melanogaster, M. musculus, and H. sapiens, that we further characterized by both in silico and in vivo approaches.
Several components of the yCCR4-associated complexes have already been identified in humans: two homologs of yPOP2 (named hCAF1 and hPOP2/hCALIF) [ 16 17 18 19 ] , and homologs of NOT proteins (named hNOT1, hNOT2, hNOT3, hNOT4) [ 19 ] . Moreover, interactions between these proteins were demonstrated [ 19 20 ] . Yet, at the present time there has been no report of a human protein that would be structurally and functionally close to yCCR4.
Firstly, we identified yCCR4 mammalian orthologs and demonstrated that the human member can interact with the human yPOP2 homologs.
Interestingly, although their C-terminal regions display significant similarity with the yCCR4 C-terminus (37%), none of these two proteins possesses a LRR domain (see Fig.