Example sentences for: xenografts

How can you use “xenografts” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We have presented data that is the first demonstration of tumor cell lines stably transfected with an ecdysone inducible constructs tested in vivo demonstrating that in vivo these constructs coupled with GS-E allow rapid and robust induction of gene expression in tumor xenografts.

  • Overrepresentation of genes involved in cell adhesion, the extracellular matrix, and vascularization among genes upregulated in cancer cells in xenografts relative to cultures

  • The efficacy and specificity of OPN, TSP-1 and TYRP-1 antibodies in IHC was tested by analysis of frozen tissue xenografts of known target gene expression [ 2 5 ] . Positive cytoplasmic staining was detected with the OPN antibody in nine of 26 (35%) primary breast carcinomas with nodal metastases.

  • Also of interest is the significant term 'Stem cells' (23,20), as similar signaling pathways are thought to regulate self-renewal in stem cells and cancer cells, and as tumors may include stem cells [ 9 ] . The entire set of enriched classes found for genes expressed more strongly in the xenografts over the cell cultures, including which genes belong to which classes, is available as additional data files and from [ 7 ] .

  • The tumor growth curves (Figure 1) illustrate the significant enhancement of the efficacy of DOX against MDA-MB 231 human breast cancer xenografts when FOC was incorporated in the diet.


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