Words similar to xenografts
Example sentences for: xenografts
How can you use “xenografts” in a sentence? Here are some example sentences to help you improve your vocabulary:
In this study, we wanted to test the hypothesis that there are changes in the breast cancer xenografts of FOC fed mice that sensitize the tumor to oxidative stress.
In the case of human tumor xenografts in a mouse host, however, it can be determined conclusively that expression of cell adhesion and ECM genes is upregulated in the cancerous cells in the tumor tissue.
Also of interest is the significant term 'Stem cells' (23,20), as similar signaling pathways are thought to regulate self-renewal in stem cells and cancer cells, and as tumors may include stem cells [ 9 ] . The entire set of enriched classes found for genes expressed more strongly in the xenografts over the cell cultures, including which genes belong to which classes, is available as additional data files and from [ 7 ] .
Although tumors are known to express high levels of genes involved in cell adhesion and the ECM, as we observed in the xenografts, assessment of the specific contribution of cancer cells to the increased expression may be difficult.
On the same two-dimensional view, we plotted one dataset of 86 profiles from lung adenocarcinomas and another dataset of 45 profiles from glioblastomas and astrocytomas, generated from previous global gene-expression studies [ 5 6 ] . Figure 1shows this principal components analysis (PCA) plot of the gene-expression profiles from cell cultures, xenografts, and human lung and brain tumors.