Example sentences for: xenografts

How can you use “xenografts” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the case of human tumor xenografts in a mouse host, however, it can be determined conclusively that expression of cell adhesion and ECM genes is upregulated in the cancerous cells in the tumor tissue.

  • In this study, we wanted to test the hypothesis that there are changes in the breast cancer xenografts of FOC fed mice that sensitize the tumor to oxidative stress.

  • The efficacy and specificity of OPN, TSP-1 and TYRP-1 antibodies in IHC was tested by analysis of frozen tissue xenografts of known target gene expression [ 2 5 ] . Positive cytoplasmic staining was detected with the OPN antibody in nine of 26 (35%) primary breast carcinomas with nodal metastases.

  • Overrepresentation of genes involved in cell adhesion, the extracellular matrix, and vascularization among genes upregulated in cancer cells in xenografts relative to cultures

  • Although tumors are known to express high levels of genes involved in cell adhesion and the ECM, as we observed in the xenografts, assessment of the specific contribution of cancer cells to the increased expression may be difficult.


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