Words similar to xenograft
Example sentences for: xenograft
How can you use “xenograft” in a sentence? Here are some example sentences to help you improve your vocabulary:
The values used in the classifications of cell culture lineage using xenograft tumor profiles, together with the classification results, which correctly predicted the lineage of all six cell culture profiles
It can therefore be concluded that, in all but a handful of genes, the numerous significant changes observed in gene expression in the xenograft tumors are due to the cancerous (human) cells and not the surrounding (mouse) host tissue.
Of the 134 genes found expressed more highly in A549 xenograft tumors over A549 cultures ( p < 0.01, fold change > 2), 70 were also higher in stage I adenocarcinomas over A549 cultures ( p < 0.05).
Expression datasets of the cell culture and xenograft profiles
The results of cell culture and animal studies have shown that omega 3 polyunsaturated fatty acids (n-3 PUFAs) selectively killed cancer cells in vitro [ 1 ] . Furthermore, n-3 PUFAs incorporated into animal diets have reduced tumor growth rates in vivo [ 2 3 4 ] . The prevailing hypothesis for the reduction in tumor cell growth, in vitro or in vivo , by supplementing the diet with high levels of n-3 PUFAs has been that the incorporation of n-3 PUFAs into cell membranes of the tumor cells increased the susceptibility of the cells for lipid peroxidation and that the products of lipid peroxidation subsequently accumulated to cytostatic or cytotoxic levels [ 2 5 6 7 ] . It has also been reported that supplementing the diet of cancer xenograft bearing mice with n-3 PUFAs could increase the efficacy of edelfosine [ 8 ] , doxorubicin [ 9 ] , mitomycin [ 10 ] , cyclophosphomide and 5-fluorouracil [ 11 ] or irinotecan [ 12 ] against the tumor.
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