Words similar to utr
Example sentences for: utr
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The longest fragments of the p27 Kip15'- UTR that have been analyzed include only the first 153 nucleotides upstream of the AUG for human [ 31 ] and 217 nucleotides for mouse [ 30 ] . It is very likely that the additional ~300 nucleotides at the 5' end of the major p27 Kip1transcript, as reported here, will play an important role in regulating p27 Kip1expression.
The existence of this 5' UTR sequence in native cDNA was confirmed by RT-PCR on RNA isolated from rabbit uterus (data not shown).
One of the families was eliminated because both L1 elements were full length, yet one of them had a 131-nucleotide insertion in its 5' UTR and the other did not, indicating that these L1s were not directly related [ 23 56 ] . Finally, for nine families, although alignment of 3'-transduced sequence with a family member was clearly delineated by the 3' TSD, we found sequence duplication in the 5' flank of the L1s.
7. It is also noted that there are 6 and 7 AUUUA motifs in 3' UTR of REP2-2.
A full-length L1 insertion in the genome is approximately 6,000 nucleotides long and consists of a 5' untranslated region (UTR), two open reading frames (ORFs), and a 3' UTR terminating in a poly(A) tail [ 11 ] . The second ORF of L1 encodes three domains critical for L1 propagation: endonuclease (EN) [ 12 ] , reverse transcriptase (RT) [ 13 14 ] , and a 3' terminal zinc-finger-like domain [ 15 ] . The EN and RT nick a target site in DNA and reverse transcribe L1 RNA, respectively, to integrate into a new genomic locus [ 12 16 17 18 ] ; this process is known as target-site-primed reverse transcription (TPRT).
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