Words similar to utrs
Example sentences for: utrs
How can you use “utrs” in a sentence? Here are some example sentences to help you improve your vocabulary:
They have long GC-rich 5'-UTRs that can form extensive secondary structure and have been classified as "weak" mRNAs because they are translated inefficiently when eIF4E levels are limiting (reviewed in [ 15 ] ). It has been proposed that when eIF4E levels are elevated these mRNAs can more effectively recruit eIF4E and its associated factors including eIF4G, a scaffold protein essential in recruiting the small ribosomal subunit, and eIF4A, a helicase essential for scanning through secondary structures in the 5'-UTR [ 15 27 ] .
The features in descending ranking were: UTRs based on known UTR indices; exons containing no ORFs or incomplete ORFs; boundaries of known full-length cDNAs (HTDB-based indices); EST orientation information (5' or 3' origin from the original IMAGE, UniGene/HINT, and dbEST databases); and Genscan-predicted poly(A) signals.
Many Drosophila genes have large introns in their 5' UTRs and these introns may not be detected if the cDNA clone from which the EST is derived is not full length; this will lead to frequent placement of the annotated TSSs too close to the ORF.
The number of genes with annotated untranslated regions (UTRs) and alternative transcripts has increased as a direct result of the increase in EST and complete cDNA sequences, and the fine details of the exon-intron structure are significantly improved.
Changes to the annotations were based largely on approximately 6,000 new 3' ESTs sequenced by the BDGP, which increased the number of genes with 3' UTRs and allowed further refinement in gene structures.
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