Words similar to untransfected
Example sentences for: untransfected
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The protein product of this gene is a member of the activating protein-1 (AP-1) family [ 19 ] , which upon binding to either c-fos or fos B protein form a complex that have high affinity to AP-1 binding concensus sequence [ 20 ] . A wide variety of chemicals, including growth factors, and tumor promotors increase the expression of this gene in various cell types [ 21 ] . Compared to untransfected keratinocytes, JunB-transfected cells grew more rapidly, and were highly invasive in an in vitro assay [ 22 ] . Therefore, the increased hepatic levels of junB gene, in mice treated with RU486, was expected to reflect an uncontrolled hepatocellular growth in these animals.
Similarly, membrane staining was observed in transfected CHO cells, but not in untransfected cells.
There was no indication of cell death in the pon A treated cultures and pon A had no effect on the untransfected parental MCF7 cell line (Fig.
Application of the labeled analogs to untransfected CHO cells did not produce membrane staining (data not shown).
IL-6 given exogenously, since LNCaP cells do not produce IL-6, resulted in increased growth of the cells concomitant with activation of STAT3 [ 36 ] . LNCaP cells transfected with a plasmid conferring constitutive IL-6 expression demonstrated increased growth, relative to untransfected or sham-transfected cells [ 36 ] . However, other investigators have observed that IL-6 treatment of LNCaP cells reulted in terminal differentiation and inhibition of growth, associated with STAT3 activation [ 17 37 38 ] . The molecular basis for the apparent contradiction is unknown at this time.
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