Example sentences for: untoward

How can you use “untoward” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, at analgesic doses, opioid receptor agonists or partial agonists can induce unwanted side effects such as ventilatory depression [ 1 2 ] and the development of physical tolerance and dependence [ 3 4 ] . Thus, the search for opioid ligands which possess analgesic effect and lack untoward effects has been a sought after goal of the medical community.

  • The latter approach would be useful in situations where the same receptor type that mediates the beneficial effect of the drug also mediates the untoward effect [ 3 ] . In this case interaction with another receptor type could reverse the unwanted effects associated with the activation of the first receptor.

  • Oxoguanine has become the benchmark for oxidative DNA modifications; it is arguably the most important mutagenic lesion in DNA (mispairing with adenine during chromosomal replications causes GC → TA transversions) [ 24 ] . It is suggested that untoward oxidative stresses to DNA prompt cell-cycle delay, antiapoptotic, and repair responses.

  • In Bridgeport, Connecticut, I have seen a Lesbia Street , which arouses all sorts of untoward speculation.

  • Given the multiplicative interactions of risk factors for thromboembolic disease and the apparently untoward concurrence of two of them—the contraceptive pill and frequent road trips for the preceding 3 y—the rapid occurrence of the clinical event following initiation of the coxib suggests a causative link to the COX-2 inhibitor.


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