Words similar to tumorigenicity
Example sentences for: tumorigenicity
How can you use “tumorigenicity” in a sentence? Here are some example sentences to help you improve your vocabulary:
Met signaling can increase tumorigenicity, induce cell motility, and enhance invasiveness in vitro and metastasis in vivo [ 14 17 18 19 20 ] . In addition, Met signaling can increase the production of protease and urokinase, which are associated with extracellular matrix/basal membrane degradation and are important for metastasis [ 14 19 ] .
BG-1 infected clones were tested for tumorigenicity by injection of cells (10 6cells in 0.1cm 250% matrigel; Collaborative Biomedical Products, Bedford, MA, USA) into subcutaneous sites in 6-week-old athymic Ncr-nude mice (NCI Animal Program, Bethesda, MD, USA) that were ovariectomized at approximately 4 weeks of age.
An increasing amount of data suggests that the RAR-β isoform, which is under the transcriptional control of RAR-α, is involved in suppressing cell growth and tumorigenicity [ 11, 12, 13, 14, 15, 16].
It is probable, however, that like tumorigenicity suppressor genes and oncogenes many more genes involved in metastasis remain to be discovered since the process is complex, involving a large number of pathways [ 4 ] . Most of the known genetic mechanisms involved in the progression of a tumor to the metastatic state involve the loss of function of genes that prevent cells from becoming invasive.
Anchorage independence analysis and tumorigenicity