Words similar to tumorigenic
Example sentences for: tumorigenic
How can you use “tumorigenic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Furthermore, TFX is inhibitory towards all tested species of Agrobacterium [ 12 ] . These results suggest that TFX production would enhance crown gall biological control for other biological control strains, such as A. rhizogenes K84, and on other host plants, especially where a mixed inoculum of different tumorigenic Agrobacterium species occurs.
Stimulation of LNCaP cell growth by RAR analog [ 33 ] and over-expression of RAR α in tumorigenic rat prostate epithelial cells [ 14 ] support the above notion.
Mutations in the IL-6 promoter region may play a role in the tumorigenic effects of constitutive IL-6 expression in prostatic carcinoma cells [ 33 ] . Such polymorphisms have been described for the IL-6 receptor in Kaposi's sarcoma, and are believed to play a role in IL-6-mediated progression of this type of cancer [ 32 ] .
There is considerable evidence to suggest that, at late stages in tumorigenesis, TGF-βs can actually promote the tumorigenic process, particularly if the epithelial cells have lost responsiveness to the growth regulatory effects of TGF-β by this time [ 9, 39, 40, 41].
For example, early investigators observed that transfection of untransformed B cells with a plasmid for constitutive expression of IL-6 conferred the tumorigenic phenotype on the cells [ 2 ] . IL-6 is a key factor in myeloma progression and survival [ 3 4 ] , and also in Kaposi's sarcoma, a solid tumor [ 5 ] . In myeloma, the standard therapy for treatment includes prednisone, which acts by inhibiting IL-6 synthesis.
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