Words similar to tumorigenic
Example sentences for: tumorigenic
How can you use “tumorigenic” in a sentence? Here are some example sentences to help you improve your vocabulary:
BRCA1 antisense subclones demonstrated other traits associated with a tumorigenic phenotype, such as the ability to grow in soft agar independent of estrogen, whereas control clones could only form colonies with the addition of estrogen.
The tumorigenic line NRP-154 expressed phospho-STAT3 under normal growth condition, while the non-tumorigenic line did not.
A characteristic phenotype of tumorigenic cells is their ability to grow anchorage-independently in suspension culture, or embedded in soft agar, without the need for attachment to the surface of a cell culture dish [ 25 26 ] . A flurry of papers has established a close link between anchorage-independent growth and the activity of several components of the cell cycle machinery, such as various cyclins, cyclin-dependent kinases (CDKs), and the CDK inhibitors p21 Cip1and p27 Kip1 [ 27 28 29 30 31 32 ] . There are indications that PTEN may be involved in these processes as well.
There is considerable evidence to suggest that, at late stages in tumorigenesis, TGF-βs can actually promote the tumorigenic process, particularly if the epithelial cells have lost responsiveness to the growth inhibitory effects of TGF-β by this time [ 9].
Elevated levels of eIF4E are associated with tumorigenic transformation and enhanced expression of specific cell cycle regulatory proteins such as cyclin D1.
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