Example sentences for: tumorigenic

How can you use “tumorigenic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • BRCA1 antisense subclones demonstrated other traits associated with a tumorigenic phenotype, such as the ability to grow in soft agar independent of estrogen, whereas control clones could only form colonies with the addition of estrogen.

  • The tumorigenic line NRP-154 expressed phospho-STAT3 under normal growth condition, while the non-tumorigenic line did not.

  • A characteristic phenotype of tumorigenic cells is their ability to grow anchorage-independently in suspension culture, or embedded in soft agar, without the need for attachment to the surface of a cell culture dish [ 25 26 ] . A flurry of papers has established a close link between anchorage-independent growth and the activity of several components of the cell cycle machinery, such as various cyclins, cyclin-dependent kinases (CDKs), and the CDK inhibitors p21 Cip1and p27 Kip1 [ 27 28 29 30 31 32 ] . There are indications that PTEN may be involved in these processes as well.

  • There is considerable evidence to suggest that, at late stages in tumorigenesis, TGF-βs can actually promote the tumorigenic process, particularly if the epithelial cells have lost responsiveness to the growth inhibitory effects of TGF-β by this time [ 9].

  • Elevated levels of eIF4E are associated with tumorigenic transformation and enhanced expression of specific cell cycle regulatory proteins such as cyclin D1.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast