Words similar to tumor-associated
Example sentences for: tumor-associated
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Identification of a stable tumor-associated immunophenotype in MF/SS allows tumor cell quantification to assess response to therapy.
Several articles describe the identification of genes associated with the activation of ECs and angiogenesis, as well as the repertoire of genes expressed in normal versus tumor-associated endothelium [ 42 43 44 45 ] . Because EC activation is a complex process, accompanied by alterations in many aspects of EC physiology, it was not surprising that the genes identified in these studies were in several functional classes.
Cancer vaccines may consist of whole tumor cells or tumor lysates, but identification of tumor-associated antigens (TAAs) over the past decade has made possible the use of specific proteins or peptides as cancer vaccines.
In addition, eight tumor-associated stromal components (including fibroblasts, endothelial cells and inflammatory cells) were microdissected from primary tumors without known metastases for analysis.
TSP-1 is a homotrimeric multidomain glycoprotein synthesized and secreted by numerous cell types, including platelets, vascular smooth muscle cells and keratinocytes [ 4 ] . Due to its interaction with a wide variety of proteins, TSP-1 has been implicated in a number of biological processes including coagulation, cell adhesion, the modulation of cell-cell and cell-matrix interactions, control of tumor growth and metastasis, and angiogenesis [ 10 ] . Inhibition of tumor cell proliferation has been achieved in vivo by systemic treatment with TSP-1 peptide mimetics [ 11 ] , but a correlation between primary tumor TSP-1 expression and poor prognosis has not been clearly established [ 12 ] . While there are reports that these molecules can originate from tumor cells [ 13 ] , the majority of reports have suggested that the major source of both TSP-1 and OPN is tumor-associated stroma [ 14 ] or infiltrating macrophages and lymphocytes [ 15 ] .
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