Example sentences for: tumor-derived

How can you use “tumor-derived” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In uncloned fibroblast populations, RNA samples from replicate cultures revealed consistent results in comparative large-scale gene expression studies [ 28 ] . Cell lines, i.e. transformed, immortalized or tumor-derived cell lines, are well known to be heteroploid i.e. chromosomally unstable, and any single-cell derived clones of such lines are genetically heterogeneous.

  • Recently, several groups have observed that chromosomal changes can lead to regional biases in gene-expression values both in yeast ( Saccharomyces cerevisiae ) and in human tumors and tumor-derived cell lines [ 2, 3, 7, 8].

  • Our assumption is in agreement with our previous findings, which have revealed that focal disruptions of ME cell layers could lead to a significantly higher proliferation rate in subjacent epithelial cells [ 12 33 ] . Our assumption is also supported by a recent study showing that normal and tumor-derived ME cells differ substantially in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition [ 37 ] . Further studies are currently in progress to elucidate the biological behavior and genetic profile of epithelial cells immediately subjacent to these SMA-negative ME cells.


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