Words similar to tumor
Example sentences for: tumor
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The T-cell activation marker CD26 was uniformly negative in tumor cells from 36 patients (81%), uniformly positive in 2 patients and showed variable positivity in 6. Thus, in 38 of 44 (86%) patients, CD4/CD26 and CD3/CD26 histograms clearly separated the phenotypically atypical T-cell populations (Figs.
These findings suggest that DAP use could be exploited in RNA samples that are limited, such as tumor biopsies.
This hypothesis is appealing because it converges on IFN-γ as a central mediator of immune regulation within the tumor microenvironment.
Our data suggests that nmt55/p54 nrbmay be critical to cell growth and function, such that, decreased nmt55/p54 nrbexpression in ER- human breast tumors or the expression of nmt55/p54 nrbvariants in ER+ tumors may indicate loss of normal growth, nmt55/p54 nrbhas been shown in several studies to bind RNA and interact with PSF and Topoisomerase I [ 14 16 17 18 19 20 39 ] . Those results along with our observations that nmt55/p54 nrbassociates with several splicing factors essential for spliceosome formation (unpublished) and relates to tumor hormonal status [ 13 ] suggest that nmt55/p54 nrbmay be involved in pre-mRNA processing.
The converse was also observed; IFNγ production at the tumor site was found to be MIG/CXCL9- and IP-10/CXCL10-dependent as indicated by the fact that neutralization of these cytokines caused a significant decrease in IFNγ(Figure 2).