Example sentences for: tss
How can you use “tss” in a sentence? Here are some example sentences to help you improve your vocabulary:
With a single EST we cannot be sure to have reached the true start site, even if it was generated by a method selecting for the cap site of the mRNA [ 17, 19]; with a cluster of ESTs within a small range, we can be more confident that we have defined the actual TSS.
The positions of the TSSs in 28 of these alignments differed by less than 10 bp and are considered identical for our purposes; in five cases, the DPD entries lie more than 10 bp upstream, and in 11 cases, a newly derived putative TSS was more than 10 bp 5' of the corresponding TSS in the DPD.
From the location distribution it is apparent that motif 1 is preferentially found close to the TSS, although not as tightly localized as the Inr motif.
However, promoter prediction is complicated by the fact that most cDNA clones do not extend to the TSS.
Recent observations have emphasized the importance of the core promoter, a region of about 100 base-pairs (bp) flanking the transcription start site (TSS), in regulating transcription [ 3, 4].