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Example sentences for: tsp-

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The efficacy and specificity of OPN, TSP-1 and TYRP-1 antibodies in IHC was tested by analysis of frozen tissue xenografts of known target gene expression [ 2 5 ] . Positive cytoplasmic staining was detected with the OPN antibody in nine of 26 (35%) primary breast carcinomas with nodal metastases.
A dose-dependent inhibition of spontaneous pulmonary metastases was reported, but this was paralleled by an inhibition of primary tumor growth [ 26 ] . TSP-1 has also been implicated in the phenomenon of concomitant tumor resistance.
Having detected all three proteins immunohistochemically in normal, benign and malignant breast epithelia, the quantitation of OPN, TSP-1 and TYRP-1 mRNA was achieved using LCM and qPCR.
TSP-1 staining was positive in two of nine primary carcinomas without metastases (22%).
We measured the expression levels of the OPN, TSP-1 and TYRP-1 genes using a quantitative PCR assay (RT-qPCR).