Example sentences for: tsp-
How can you use “tsp-” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our LCM-mediated transcript detection acts as an important confirmation of breast tumor cell OPN synthesis because IHC analysis does not rule out the possibility that secreted proteins such as OPN and TSP-1 are sequestered by the tumor cells from the local environment.
Our finding that AGE-BSA and PA induce apoptosis through a CD36-mediated and p38- and caspase-dependent mechanism in tubular epithelial cells, similar to TSP-1 and ox-LDL in endothelial cells and macrophages, respectively, suggests that multiple, context-dependent extracellular stimuli of apoptosis may converge on CD36 scavenger receptor to activate src kinase and proapoptotic p38 MAPK pathway.
In line with the OPN patterns of expression, there was no significant difference in TSP-1 levels between primary tumors with or without metastases, nor between primary carcinomas and associated metastases.
The precise biological role of TSP-1 in human tumor progression awaits more definitive study.
CD36 is widely expressed and may interact with multiple extracellular ligands, including thrombospondin-1 (TSP-1), long-chain free fatty acids (FFAs), modified (oxidized) low-density lipoprotein (ox-LDL), advanced glycation end (AGE) products, and collagens I and IV [6].