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Example sentences for: tsds

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To test whether the inversion breakpoints occur at a conserved distance from the 5' or 3' ends of the L1 elements, the start and the end positions of the 5' inverted L1 segment were compared using a scatterplot diagram for each inverted L1 with TSDs (Figure 6a).
Interestingly, symmetrical, but much less dramatic, peaks of T and A nucleotides are seen near the 3' end of the 15-nucleotide-long TSDs.
To investigate this, we segregated our set of L1s with TSDs into the following major classes of structural variants and analyzed their respective TSDs: 5' truncated, 5' inverted, or full-length (L1 start ≥ 10) standard insertions, and 3' transduction candidates (Figure 1b).
Indeed, the TSDs for the 3'-transduction events that lack a polyadenylation signal are A-rich at their 5' ends (Table 1), indicating that the target site at which priming occurred would have been T-rich.
Identification of L1s and TSDs