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Example sentences for: tsgs

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3 that harbor putative TSGs important in CC development providing a basis for their identification.
A nonrandom pattern of promoter hypermethylation has been noted in specific genes in specific tumor types, although some genes are commonly methylated in diverse tumors [ 3 4 ] . The extent of aberrant promoter hypermethylation and its association with loss of gene function in cancer suggests that CpG island methylation is an important mechanism in inactivating tumor suppressor genes (TSGs).
The pattern of such promoter methylation has been noted to be non-random in various tumor types, while certain genes are commonly methylated in diverse tumor types [ 10 11 ] . The extent of aberrant promoter hypermethylation and its association with loss of gene function in cancer suggests that CpG island methylation is an important mechanism in inactivating tumor suppressor genes (TSGs).
3 also were affected by LOH and exhibited loss of expression in teratoma [ 9 ] . The BTG1 , APAF1 , and NEDD1 genes mapped to the 12q22 common-deletion region, and thus considered as candidate TSGs in GCT [ 8 10 11 ] .
3 interval suggests that they may be target TSGs of these deletions in CC.