Words similar to tsd
Example sentences for: tsd
How can you use “tsd” in a sentence? Here are some example sentences to help you improve your vocabulary:
In cases where multiple TSDs were identified, TSDs with the best score and with a candidate poly(A) tail immediately preceding the 3' HSP were defined as the TSD for a particular L1 insertion.
This finding, combined with generally high TSD scores and manual inspection of hundreds of L1s recovered, gives us confidence that the sequences identified by the TSDfinder algorithm represent actual TSDs.
The algorithm for TSD signature recognition allows for detection of both 'standard' insertion events (in which the 3' TSD immediately follows the poly(A) tract associated with the retrotransposon) and possible 3' transduction events (in which the 3' TSD follows a poly(A) tail further downstream from the retrotransposon 3' end).
The first and the last 15 nucleotides of the L1 itself are also included in the TSD search to allow for some L1 boundary imprecision.
To investigate this, we recreated pre-insertion loci by collecting 50 nucleotides of upstream and downstream flanking sequence and the TSD sequence of each L1 insertion for which a high-scoring TSD was found.