Words similar to tsd

Example sentences for: tsd

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To investigate this, we recreated pre-insertion loci by collecting 50 nucleotides of upstream and downstream flanking sequence and the TSD sequence of each L1 insertion for which a high-scoring TSD was found.
These TSDs were selected by the TSDfinder program in part because the 3' TSD was preceded by a poly(A) tail (see Materials and methods).
For five of the transduced sequences lacking a clear polyadenylation signal, the alignment between the 3'-transduced sequence and family members ended at an A-rich sequence; the 3' TSD of the 3'-transduction event was found immediately downstream of this A-rich sequence in the DNA (Figure 3b).
The peak of nine-nucleotide TSDs, the minimum TSD length allowed by TSDfinder, is likely to be enriched in false positives because they have a relatively low average TSD score of 98; there is obviously a higher likelihood of finding these shorter matches by chance.
To be classified as an L1-TD, the distance between the end of the L1 3' UTR and the start of the 3' TSD had to be greater than 20 nucleotides (not counting the length of the poly(A) tail preceding the TSD nor the number of nucleotides missing from the end of the L1 3' UTR according to the RepeatMasker annotation of the L1 element).