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Example sentences for: tsdfinder
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Finally, we observed that for two of the L1-TDs that do not have a polyadenylation signal, the sequence that the TSDfinder program defined as the poly(A) tail is 'patterned'; that is, the tail is composed of A-rich simple repeats (for example, AAATAAAT.
These TSDs were selected by the TSDfinder program in part because the 3' TSD was preceded by a poly(A) tail (see Materials and methods).
To facilitate this study, we wrote the software TSDfinder, which identifies the TSDs, poly(A) tails, and inversion breakpoints (if any) associated with L1s.
Next, TSDfinder found the poly(A) tail and TSDs, critical components of the insertion signature of an L1.
The range of poly (A) tail lengths found by TSDfinder was 10-85 nucleotides.