Words similar to triterpenoid
Example sentences for: triterpenoid
How can you use “triterpenoid” in a sentence? Here are some example sentences to help you improve your vocabulary:
CDDO is an early-generation synthetic triterpenoid, and further modifications continue to be made.
utilis) that produce a dose-related increase in the clotting time of blood induced by carpet viper venom ( Echis carinatus ) would be useful against bites from Bothrops species that cause haemorrhage at the point of injection due to the inhibition of the clotting mechanism [ 40 ] . Antivenom compounds so far isolated from plants include protocatechuic acid, a catechin-gallo-catechin tannin, caffeic acid derivatives (chlorogenic acid, cynarin), coumarins (bergapten), flavonoids (rutin, isoscutellarein, kaempferol, quercetin, hesperidin), ar-turmerone, alkaloids (aristolochic acid), triterpenoids, triterpenes, coumestans (wedelolactone), sterols (sitosterol, stigmasterol, beta-amyrin), triterpenoid glycosides, alkaloids (allantoin) and lignoflavonoids [ 43 40 44 42 ] . Many relevant compounds are widely distributed nitrogen-free, low molecular weight compounds (except aristolochic acid, an untypical non-basic, nitro-derivative) [ 38 ] . The structural similarities of certain plant chemicals found in plants used for snakebites are an isoflavone skeleton, acidic nature and dioxygenated functionality [ 44 ] .
MMP-1 and MMP-13 have been identified as the significant enzymes involved in this process in vivo . We examined a novel, synthetic triterpenoid, CDDO, as a potential inhibitor of collagenase expression.
Triterpenoids are a novel family of steroid-like compounds with weak anti-inflammatory properties [ 18 ] . Synthetic triterpenoids have been produced with the aim of achieving increased potency [ 19 20 ] . 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO) is a synthetic triterpenoid that has been shown to inhibit expression of the inflammatory genes inducible nitric oxide synthase and cyclo-oxygenase-2 [ 20 21 22 ] . In a recent report, MMP-1 and MMP-13 expression were induced with IL-1, a known pro-inflammatory mediator in vivo in joint tissues [ 23 ] . It was shown that CDDO could inhibit the IL-1-induced expression of these pro-inflammatory MMPs.
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