Example sentences for: triphosphate

How can you use “triphosphate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The metal cations direct a 5' nucleoside triphosphate to form a phosphoester bond with the 3' hydroxyl of the preceding nucleotide (the 3'-terminal nucleotide of a growing polynucleotide chain), with the elimination of pyrophosphate [ 6 ] .

  • CO may also be decreased in adrenal insufficiency as the result of the myofibrillar adenosine triphosphate (ATP) depletion seen with glucocorticoid deficiency [ 20].

  • Commercially available 2-aminoadenosine-5'-triphosphate, 5-methylcytidine-5'-triphosphate, and 5-methyluridine-5'-triphosphate (TriLink Biotechnologies, Inc., San Diego, CA) were substituted for ATP, CTP, and UTP, respectively, in separate reactions containing either complete substitution, 1:1, or 1:3 ratio of modified: unmodified NTP, keeping molar input of nucleotide constant.

  • Resistance to acyclovir (ACV) or penciclovir (PCV) generally arises by a single base mutation in either the HSV thymidine kinase (TK) or DNA polymerase (Pol) gene [for a review, see reference [ 5 ] ]. Unlike Pol, TK is not essential for virus replication in cell culture [ 7 ] , although in vivo analyses implicate it in HSV virulence, pathogenicity and reactivation from latency [ 4 8 16 22 ] . Since ACV and PCV are dependent upon HSV TK for monophosphorylation, an event obligatory for the formation of the active triphosphate inhibitor [ 14 ] , ACV risolates often exhibit high levels of cross-resistance to PCV [ 2 3 ] .

  • Cyclic AMP generation and thiamine triphosphate hydrolysis appear to be secondarily acquired activities.


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