Words similar to triphosphatases

Example sentences for: triphosphatases

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The key question is whether RNA triphosphatase is a valid drug target in other fungal species besides Saccharomyces cerevisiae (which is not a human pathogen) and whether a mechanism-based inhibitor of one fungal RNA triphosphatase could be expected to display broad spectrum activity against triphosphatases from other fungal species.
This is not a straw-man issue, given that S. cerevisiae encodes two homologous RNA triphosphatases (Cet1 and Cth1), of which only Cet1 is essential for capping and cell viability [ 8 15 ] . We use classical genetic approaches to show that the respective genes encoding RNA triphosphatase and RNA guanylyltransferase are essential in S. pombe.
Further iterations, run to convergence, recovered the soluble mammalian thiamine triphosphatases (3 × 10 -4), and the N-terminal region of E. coli YgiF.
These observations, taken together, suggested that CyaB and soluble mammalian thiamine triphosphatases define a novel superfamily of conserved domains, which may either occur by itself or in combination with other domains.
Thus, we suspect that all fungal species will have metal-dependent RNA triphosphatases resembling those of S. cerevisiae, C. albicans and S. pombe.