Words similar to transactivator
Example sentences for: transactivator
How can you use “transactivator” in a sentence? Here are some example sentences to help you improve your vocabulary:
Approximately 10,000 males bearing a new PdL insert and an rtTA transcriptional transactivator insertion were generated.
The generation of Hoxc-8 transgenic mice and the characterization of their phenotype have been published [ 1 ] . Briefly, Hoxc-8 expressing mice are generated in a binary transgenic mouse system [ 44 ] by crossing a transactivator strain (harboring a transgene in which expression of the transcriptional transactivator VP16 is under control of the Hoxc-8 promoter; [ 45 ] ) to a transresponder strain (that carries as a transgene the Hoxc-8 cDNA linked to the ICP4 immediate early gene promoter, which is silent in mice in the absence of VP16; [ 45 46 ] ). Upon combination of both transgenes, the Hoxc-8 transresponder transgene is activated, and Hoxc-8 becomes overexpressed [ 23 ] . This system also allows the generation of transgenic mice with increased gene dosage by superimposition of transgene loci to homozygosity [ 23 44 ] . For the studies reported here, we used the T239 transactivator and the IE-c8-254 transresponder strains.
A direct effect would imply that a CMV transactivator is produced that could somehow cause the expression of or at least aid in the activation of the BZLF1 gene.
Strains homozygous for the transgenic constructs were crossed to rtTA(3)E2 strain, homozygous for the rtTA transactivator construct, to generate progeny heterozygous for both constructs [ 1].
Calcium-dependent Ca 2+ /calmodulin kinase activity is also upregulated by slow motor neuron activity, possibly because it amplifies the slow-type calcineurin-generated responses by promoting MEF2 transactivator functions and enhancing oxidative capacity through stimulation of mitochondrial biogenesis (Wu et al.
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