Words similar to transactivator
Example sentences for: transactivator
How can you use “transactivator” in a sentence? Here are some example sentences to help you improve your vocabulary:
The SV40-transformed BS cell line GM0855B (blm Ash[2281Δ6ins7]/ bim Ash [2281Δ6ins7]) [ 3] was transfected with a plasmid expressing the tetracycline or doxycycline (Tet)-responsive transcriptional transactivator from a CMV promoter [ 32].
In the rtTA transgenic construct the powerful and tissue-general actin5C promoter drives expression of the rtTA transcriptional transactivator [ 33].
The transcriptional transactivator (Tat) is a key regulatory protein of HIV.
As shown in Figure 2A, 24 hr incubation with doxycycline in the medium has no appreciable effect on endogenous PP1α protein expression in the untransfected parent cell line (UMUC3) or a cell line transfected with the reverse tetracycline transactivator plasmid pUHD172-1neo only (LLWO1).
The generation of Hoxc-8 transgenic mice and the characterization of their phenotype have been published [ 1 ] . Briefly, Hoxc-8 expressing mice are generated in a binary transgenic mouse system [ 44 ] by crossing a transactivator strain (harboring a transgene in which expression of the transcriptional transactivator VP16 is under control of the Hoxc-8 promoter; [ 45 ] ) to a transresponder strain (that carries as a transgene the Hoxc-8 cDNA linked to the ICP4 immediate early gene promoter, which is silent in mice in the absence of VP16; [ 45 46 ] ). Upon combination of both transgenes, the Hoxc-8 transresponder transgene is activated, and Hoxc-8 becomes overexpressed [ 23 ] . This system also allows the generation of transgenic mice with increased gene dosage by superimposition of transgene loci to homozygosity [ 23 44 ] . For the studies reported here, we used the T239 transactivator and the IE-c8-254 transresponder strains.
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