Example sentences for: transactivator

How can you use “transactivator” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A direct effect would imply that a CMV transactivator is produced that could somehow cause the expression of or at least aid in the activation of the BZLF1 gene.

  • pUHD172-1neo [ 25 ] encodes the reverse tetracycline transactivator protein fused with a nuclear localization signal (rtTA-nls).

  • The SV40-transformed BS cell line GM0855B (blm Ash[2281Δ6ins7]/ bim Ash [2281Δ6ins7]) [ 3] was transfected with a plasmid expressing the tetracycline or doxycycline (Tet)-responsive transcriptional transactivator from a CMV promoter [ 32].

  • As shown in Figure 2A, 24 hr incubation with doxycycline in the medium has no appreciable effect on endogenous PP1α protein expression in the untransfected parent cell line (UMUC3) or a cell line transfected with the reverse tetracycline transactivator plasmid pUHD172-1neo only (LLWO1).

  • In addition, BRCA1 can act as a transcriptional transactivator in yeast reporter assays [ 26, 27] and binds the RNA polymerase II holoenzyme, a component of the basal transcription machinery [ 25].


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