Words similar to transactivator
Example sentences for: transactivator
How can you use “transactivator” in a sentence? Here are some example sentences to help you improve your vocabulary:
pUHD172-1neo [ 25 ] encodes the reverse tetracycline transactivator protein fused with a nuclear localization signal (rtTA-nls).
A direct effect would imply that a CMV transactivator is produced that could somehow cause the expression of or at least aid in the activation of the BZLF1 gene.
An SV40-transformed BS cell line (GM0855B) was transfected with a plasmid containing an expression unit for the tetracycline or doxycycline (Tet) responsive transcriptional transactivator [ 32].
The SV40-transformed BS cell line GM0855B (blm Ash[2281Δ6ins7]/ bim Ash [2281Δ6ins7]) [ 3] was transfected with a plasmid expressing the tetracycline or doxycycline (Tet)-responsive transcriptional transactivator from a CMV promoter [ 32].
The generation of Hoxc-8 transgenic mice and the characterization of their phenotype have been published [ 1 ] . Briefly, Hoxc-8 expressing mice are generated in a binary transgenic mouse system [ 44 ] by crossing a transactivator strain (harboring a transgene in which expression of the transcriptional transactivator VP16 is under control of the Hoxc-8 promoter; [ 45 ] ) to a transresponder strain (that carries as a transgene the Hoxc-8 cDNA linked to the ICP4 immediate early gene promoter, which is silent in mice in the absence of VP16; [ 45 46 ] ). Upon combination of both transgenes, the Hoxc-8 transresponder transgene is activated, and Hoxc-8 becomes overexpressed [ 23 ] . This system also allows the generation of transgenic mice with increased gene dosage by superimposition of transgene loci to homozygosity [ 23 44 ] . For the studies reported here, we used the T239 transactivator and the IE-c8-254 transresponder strains.
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