Words similar to transactivation
- transaction
- transactionalism
- transactionaverage
- transactions
- transactions--intragovernmental
- transactions—from
- transactivate
- transactivates
- transactivating
- transactivation
- transactivator
- transactivators
- transacylation
- transalphabetism
- transamerica
- transamidation
- transatlanguage
- transatlantic
- transblot
- transbronchial
- transit-lt
Example sentences for: transactivation
How can you use “transactivation” in a sentence? Here are some example sentences to help you improve your vocabulary:
The rexinoid alone has no effect on transactivation of the βRARE, but strongly inhibits responses to both the agonist TCPOBOP and the inverse agonist androstanol.
p20-C/EBPβ lacks the N-terminal transactivation domain and therefore acts as a repressor of transcription.
Released NF-κB dimers then translocate to the nucleus, bind to its cognate DNA elements, and induce the expression of target genes [ 23 24 25 ] . Activated, nuclear translocated, NF-κB transcription factor has been documented in the mouse embryo from the 1-cell stage onward [ 26 27 ] . Activated NF-κB translocation into the nucleus, directly or indirectly, effects the transcriptional control of over 150 target genes [ 28 ] . NF-κB enhances cell proliferation by stimulating the expression of cytokines such as TNF, IL-1, IL-2, IL-6, and IL-8, among others [ 28 29 ] ; NF-κB inhibits apoptosis by inducing TRAF and clAP expression which suppresses Caspase 8 activation [ 30 ] , and by inhibition of p53 transactivation [ 31 32 ] .
For FOXC1 and PAX6, both haploinsufficiency and increased gene dosage due to gene duplication result in abnormal ocular development [ 10 11 12 13 ] . Similarly, a mutation in PITX2 that results in increased transcriptional transactivation causes ASD [ 14 ] .
Further characterization of potential CAR cofactors, as well as the development of sensitive and direct ligand binding assays will be required to define the molecular mechanisms that account for the diverse effects of rexinoids on CAR transactivation.
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