Words similar to transactivating

Example sentences for: transactivating

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, the DNA-binding elements and the transactivating portion of the molecule (or complex) do not require precise positioning with respect to each other).
An NMR structure for the lexA DNA-binding domain has been presented [ 26 ] . The structure is compact and globular, and probably interferes only minimally with fused transactivating sequences.
The main USF isoforms USF1 (43 kDa) and USF2 (44 kDa) are ubiquitously expressed and encoded by separate genes [ 9 10 11 ] . In addition, more isoforms of USF2 are produced due to alternative splicing and utilization of different translation start sites [ 12 13 ] . USF factors exist as homo and heterodimers, and the heterodimer of USF1/USF2a seems to dominate, although there are cell-type specific variations [ 12 ] . USF1 and USF2 show different transactivating potential, and USF2 appears to be the functional transactivator of the GIRE complex, although both USF1 and USF2 are important for sustained dietary-induced expression of the fatty acid synthase gene in liver [ 14 ] .
and, (ii) what is the significance of the extreme sequence diversity evidenced by transactivating peptides?
USF1 and USF2 display identical dimerization and DNA binding domains, but the transactivating regions differ [ 25 ] . USF1 and USF2 obviously serve different, yet overlapping functions, and regulating the relative USF1/USF2 levels may be decisive for the pattern of USF-mediated gene expression, which has been shown in studies of USF knockout mice.