Words similar to tk
Example sentences for: tk
How can you use “tk” in a sentence? Here are some example sentences to help you improve your vocabulary:
Two-hybrid protein-protein interaction assays were performed in Hela cells, with a reporter plasmid (pG4-TK-Luc) containing six GAL4 binding elements upstream of the thymidine kinase (TK) promoter region fused to the luciferase reporter gene (Fig.
The targeting vector also contains the HSV TK gene to allow for negative selection of non-recombinants.
However, alignment of the tk sequences showed that the type 2 gene had at least eight distinct stretches containing between 7 and 13 G-C bases, whereas the overlapping region in the type 1 tk had four or less G-C bases.
The demonstration of S1 nuclease-sensitive sites within the type 2 viral genome overlapping the tk coding region, and the absence of such sites in the type 1 viral genome, suggest that local topology may be different between these HSV-1 and HSV-2.
Thus, the high proportion of errors associated with HSV-2 viruses appears specific to the tk mutagenesis assay.
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