Example sentences for: thymocytes

How can you use “thymocytes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It has been well documented that thymocytes in adult Rag1 or Rag2 mutants have dramatically reduced proliferation compared to wild type, particularly at the TN3 stage [ 37 38 39 40 ] , and Penit et al.

  • Therefore, nearly every stage from the earliest TN to the DP stages showed significantly increased proliferation in fetal thymocytes relative to adults.

  • 1. Thymocytes undergo selection in the thymic parenchyma, and in the case of negative selection, the selecting elements appear to be derived from the bone marrow and consist mainly of thymic dendritic cells.

  • Cholesterol oxides are also toxic to cells derived from the immune system, such as macrophages, thymocytes, lymphoma cells and leukemic T-cells.

  • There is considerable evidence that thymopoiesis differs in the fetal thymus during the initial creation of the microenvironment, as opposed to adult thymus function (reviewed in [ 47 ] ). Differences have been reported in responses to some cytokines, in signaling at the TN-DP transition in fetal compared to adult thymus, and in proliferation of CD4 +SP thymocytes [ 36 48 49 50 ] . The proliferation profiles of both wild type and Rag -/-fetal thymocytes support the hypothesis that fetal thymocyte maturation is fundamentally different from thymocyte development in the adult thymus.


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