Words similar to thymocyte
Example sentences for: thymocyte
How can you use “thymocyte” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thymocytes in the adult Rag1 -/-thymus have been previously shown to have overall lower levels of proliferation than adult wild type TN thymocytes [ 13 ] , particularly at the TN3 stage [ 37 38 39 40 ] . At fetal stages, our results showed that proliferation also varied between thymocytes in the wild type and Rag1 -/-thymus at discrete stages of thymocyte differentiation.
There is considerable evidence that thymopoiesis differs in the fetal thymus during the initial creation of the microenvironment, as opposed to adult thymus function (reviewed in [ 47 ] ). Differences have been reported in responses to some cytokines, in signaling at the TN-DP transition in fetal compared to adult thymus, and in proliferation of CD4 +SP thymocytes [ 36 48 49 50 ] . The proliferation profiles of both wild type and Rag -/-fetal thymocytes support the hypothesis that fetal thymocyte maturation is fundamentally different from thymocyte development in the adult thymus.
Although differences in the proliferation of fetal vs. adult TCR-expressing thymocytes and have been reported [ 36 ] , we were interested in investigating the more immature thymocyte subsets.
In purifying thymocyte subsets, there is a risk that the antibodies used for the selection of the DP subset can stimulate cells through a TCR-like signaling, thus masking the read-out of the experimental stimuli and; (c) At least 80% of thymocytes are double positive (DP) cells.
For example, SCF and IL-7 have been shown to have synergistic functions [ 62 63 ] . Therefore, changes in multiple cytokines in Hoxa3 +/- Pax1 -/-mutants would be expected to have complex effects on thymocyte development that could be difficult to predict.
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