Example sentences for: thymic

How can you use “thymic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mounting evidence suggests that the pre-TCR does not require interaction with a ligand to perform its function, and the subsequent CD44 -25 -(TN4 or pre-DP) to DP transition has been termed "programmed differentiation" to indicate that this step can occur in isolated thymocytes, presumably without input from extrinsic signals [ 25 26 27 ] . However, there is also evidence that the thymic microenvironment does contribute signals required for the TN-DP transition, particularly to promote thymocyte proliferation and apoptosis [ 13 28 29 30 ] . The specific nature and purpose of the TEC contribution during this important transition therefore remains to be determined.

  • This would lead to a situation where T cells may undergo thymic maturation without having been negatively selected for antigens that are expressed on the predominantly inactive X chromosome.

  • The most profound form of T-cell tolerance involves deletion of potentially self-reactive T cells during thymic selection.

  • Interestingly, thymic epithelial cells appear to be derived from very few founder cells [ 18], and thus should exhibit a rather large degree of `patchiness' with respect to X inactivation.

  • 2. Thymocytes undergo selection in the thymic parenchyma and, in the case of negative selection, the selecting elements appear to be derived from the bone marrow and consist mainly of thymic dendritic cells.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast