Example sentences for: thymic

How can you use “thymic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thymic lobes were dissected from E15.

  • However, in the thymus a splice variant results in the lack of thymic expression of an immunodominant peptide.

  • Nevertheless, these data illustrate the potential importance of deficiencies in thymic deletion for autoimmune T-cell reactivity.

  • Mounting evidence suggests that the pre-TCR does not require interaction with a ligand to perform its function, and the subsequent CD44 -25 -(TN4 or pre-DP) to DP transition has been termed "programmed differentiation" to indicate that this step can occur in isolated thymocytes, presumably without input from extrinsic signals [ 25 26 27 ] . However, there is also evidence that the thymic microenvironment does contribute signals required for the TN-DP transition, particularly to promote thymocyte proliferation and apoptosis [ 13 28 29 30 ] . The specific nature and purpose of the TEC contribution during this important transition therefore remains to be determined.

  • The most profound form of T-cell tolerance involves deletion of potentially self-reactive T cells during thymic selection.


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