Words similar to thr

Example sentences for: thr

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Like other steroid hormone receptors, GRs are phosphoproteins, and reversible phosphorylation of specific ser/thr residues on the GR or associated proteins has been implicated in the regulation of 1) hormone binding to the cytoplasmic GR-complex, 2) the translocation of the GR between the cytoplasm and the nucleus, 3) the binding of ligand activated GR to consensus GRE in the promoter regions of GR-responsive genes, and 4) the formation of an active transcriptional complex [ 1, 2, 5, 6, 7, 8, 28, 29, 30, 31].
The target for this Ras stimulation is Thr235 in a consensus MAPK site in C/EBPβ [ 23].
Several possible structural explanations for poor repression by T59S were offered: 1. The loss of the Thr59 methyl group results in a reduction of hydrophobic interaction area of 25Å 2(out of 700 Å 2total).
At last, beta-2 Thr83 is rather remote from the ligands (8.
Variations at residues alpha4 Thr183 and beta2 Ala135 generate different shapes of the binding pocket (Figure 4- Top), but preserve the electrostatic potential of the system: all non-conserved residues at position 183 are hydrophobic, and hydroxyl of Thr154 and Ser154 are superimposed, pointing away from the ligand, towards the carboxylate of Asp122.