Example sentences for: tgf-β

How can you use “tgf-β” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Though the role of TGF-β has been correlated with drug induced nephrotoxicity [ 29 ] it is early to speculate if this combination will also result in an increased nephrotoxic effects.

  • There is considerable evidence to suggest that, at late stages in tumorigenesis, TGF-βs can actually promote the tumorigenic process, particularly if the epithelial cells have lost responsiveness to the growth regulatory effects of TGF-β by this time [ 9, 39, 40, 41].

  • TGF-β1 blocked this increased sensitivity.

  • It has been speculated that intra-articular delivery of TGF-β1 would result in enhanced synthesis of new matrix [ 9 ] . Indeed, we have reported previously that the TGF-β1 gene is more effective than insulin-like growth factor type 1 and bone morphogenetic protein type 2 genes in stimulating new matrix synthesis from rabbit chondrocytes in culture.

  • These data are consistent with conclusions from previous studies indicating that dendrite-promoting activity is restricted to BMPs from the 60A or dpp (BMPs 2 and 4) subgroups and is not observed with BMPs from other subgroups such as BMP-3, BMP-13 or dorsalin, or with other members of the TGF-β superfamily such as activin, TGF-β1, -β2 or -β3 [ 16 17 ] . Functional redundancy between BMPs of the 60A subgroup has been previously reported with respect to other developmental endpoints [ 6 ] , of which some, such as upregulation of cell adhesion molecules [ 30 ] , may be directly relevant to effects on dendritic growth.


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