Words similar to tgf
Example sentences for: tgf
How can you use “tgf” in a sentence? Here are some example sentences to help you improve your vocabulary:
Recently, a subset of CD4 +T cells was identified that is present on 5-10% of CD4 +T cells in normal naïve mice and expresses CD25 (the α-chain of IL-2 receptor) [ 4 5 ] . Functional analysis of murine CD4 +CD25 +T cells showed that those cells, which constitutively express cytotoxic T-lymphocyte antigen (CTLA)-4 [ 6 7 8 ] , fail to proliferate or secret cytokines in response to polyclonal or antigen-specific stimulation, but inhibit the activation of conventional responsive T cells [ 1 2 3 8 9 ] . The suppressive activity of the CD4 +CD25 +T cells depends on signaling via the negative regulator of T-cell activation CTLA-4 [ 7 ] and requires a cell-cell interaction that possibly involves cell surface bound transforming growth factor (TGF)-β 1 [ 1 10 ] . It has been shown that B7/CD28 costimulation is essential for the development and homeostasis of the CD4 +CD25 +regulatory T cells [ 6 ] , which play critical roles not only in preventing autoimmunity but also in controlling tumor immunity and transplantation tolerance [ 2 11 ] .
Intra-articular injection of adenoviral vector expressing human transforming growth factor (Ad.TGF)-β1 resulted in a high level of TGF-β1 accumulation in the synovial fluid.
The one used most often (SH-2) was recently shown to react with endoglin (CD105), a member of the transforming growth factor (TGF)-β receptor family usually found on the endothelium of postcapillary venules [ 4].
Ad.Luc = adenoviral vector expressing luciferase; Ad.TGF = adenoviral vector expressing human transforming growth factor; AIA = antigen-induced arthritis; ELISA = enzyme-linked immunosorbent assay; GAG = glycosaminoglycan; H & E = hematoxylin and eosin; IL = interleukin; TGF = transforming growth factor.
AICD = activation-induced cell death; CTLA = cytotoxic T-lymphocyte antigen; ELISA = enzyme-linked immunosorbent assay; FITC = fluorescein isothiocyanate; IL = interleukin; PE = R-phycoerythrin; PG = proteoglycan; PGIA, proteoglycan-induced arthritis; SCID = severe combined immunodeficient; TCR = T-cell receptor; TGF = transforming growth factor; WT = wild-type.
Loading...