Example sentences for: tetrameric

How can you use “tetrameric” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Analysis of the crystal structure of GlpF suggests that potential ion binding sites may be located in the central pore, at the four-fold axis of symmetry in the tetrameric association of subunits that form the channel [ 15 ] . Interestingly, this arrangement of a tetramer of subunits to form a central ion pore is a hallmark of the family of voltage-gated ion channels [ 23 ] , which rely on a tetrameric organization to create a central pore for ions that is lined by sequences contributed from all four subunits.

  • PerCP-conjugated anti-CD3e (Pharmingen, San Diego, CA) and FITC-conjugated anti-CD8 (Becton Dickinson, San Jose, CA) were used in conjunction with the tetrameric complexes.

  • Nearly all intermediate filament proteins exhibit a highly conserved amino acid motif (YRKLLEGEE) at the C-terminal end of their central alpha-helical rod domain which has been shown to be crucial for the formation of authentic tetrameric complexes and for the control of filament width [ 43 ] .

  • Staining with tetrameric complexes was done afterward as described above.

  • Cyclic nucleotide-gated channels, for example, appear to exhibit functional dimerization of their cyclic nucleotide-binding domains [ 32 ] . The "RCK" domain of BK channels has a dimerization domain even though BK channels, too, are tetrameric at the level of the pore [ 33 ] . Finally, the GluR2 ligand-binding core has a dimerization interface in the crystal structure [ 34 ] . Evidence, including the clustering of residues involved in receptor desensitization at this interface, suggests that the dimerization is not just crystallographic but functional.


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