Example sentences for: tetramer-positive

How can you use “tetramer-positive” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The directly isolated tetramer-positive T cells from this patient specifically lysed T2 cells pulsed with high concentrations (1 μg/ml) of G209–2M and native (G209n) peptides, but not with T2 cells pulsed with a cytomegalovirus-derived, HLA-A*0201-restricted peptide (NLVPMVATV) or melanoma targets.

  • CD8+ tetramer-positive T cells were sorted under sterile conditions into 96-well plates, one cell per well, using a FACS Vantage (Becton Dickinson).

  • All six TAA-specific populations exhibited robust functional responses ex vivo, as measured by percentage of G2090–2M- and M26-tetramer-positive cells that mobilized CD107 and/or downregulated the CD3 complex upon incubation with T2 cells pulsed with cognate peptides (Table 1; 86%-99.

  • The finding of a higher percentage of tetramer-positive CD8+ T-cells in tissues of macaque 819, infected intravenously, than in animal 817, infected intrarectally, may reflect a higher rate of viral replication in tissues of this animal at the time of sacrifice.

  • Randomly selected expanding clones and the tetramer-positive population from which they were derived were examined for TCR VB expression using TCR VB-specific monoclonal Abs and VB-specific primers in PCR.


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