Words similar to tetramer-positive

Example sentences for: tetramer-positive

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All six TAA-specific populations exhibited robust functional responses ex vivo, as measured by percentage of G2090–2M- and M26-tetramer-positive cells that mobilized CD107 and/or downregulated the CD3 complex upon incubation with T2 cells pulsed with cognate peptides (Table 1; 86%-99.
The directly isolated tetramer-positive T cells from this patient specifically lysed T2 cells pulsed with high concentrations (1 μg/ml) of G209–2M and native (G209n) peptides, but not with T2 cells pulsed with a cytomegalovirus-derived, HLA-A*0201-restricted peptide (NLVPMVATV) or melanoma targets.
A large number of clonal CTL lines (more than 200) were generated by FACS of individual G209–2M- and M26-tetramer-positive cells directly from PBMC samples (Table 2).
Prior to each cytotoxicity assay, clones underwent ficoll-hypaque centrifugation to remove dead feeder cells and were determined to be greater than 80% CD8+ tetramer-positive T cells by FACS.
The finding of a higher percentage of tetramer-positive CD8+ T-cells in tissues of macaque 819, infected intravenously, than in animal 817, infected intrarectally, may reflect a higher rate of viral replication in tissues of this animal at the time of sacrifice.