Example sentences for: tetramer

How can you use “tetramer” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Lymphocytes were identified by forward and side scatter signals, then selected for CD8+ and tetramer positive.

  • The bacterial K +channel KcsA, whose X-ray crystal structure has been solved and is definitively a tetramer [ 30 ] , runs as a tetramer on SDS gels [ 31 ] . Furthermore, mutations that disrupt a known intersubunit interface at the level of the pore disrupt this biochemical tetramerization.

  • Their findings also bring into question the ability to deduce the recognition efficiency and tumor reactivity of T cell responses from ELISPOT and tetramer staining assays—the two standard measures of T cell responses to vaccines—which has implications for rational vaccine design in general.

  • Although staining with peptide–MHC tetramers provides a direct estimate for the number of TAA-specific T cells present in vivo, and intensity of tetramer staining has been employed as a parameter for isolation of high-RE, tumor-lytic T cells [27], staining intensity does not correlate well with RE or tumor-lytic potential [28,29], and cannot be considered a reliable indicator for the functional status of TAA-specific T cells.

  • For example, of the nine clones analyzed from patient 517, none were efficient in tumor cell lysis, yet these cells were detectable by MHC tetramer staining.


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