Words similar to tetramers

Example sentences for: tetramers

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Peptide specificity and CD8 expression of each clone was confirmed by staining with G209–2M- and M26-tetramers and anti-CD8 monoclonal Ab (data not shown).
A 50% decrease in p53 monomers can easily be imagined to result in a greater than 50% decrease in functional tetramers, which in turn increases the chances of these cells becoming cancerous.
For those ion channels within this superfamily for which stoichiometry has been directly examined, all have been shown to be composed of four six-transmembrane domain subunits or pseudosubunits, with auxiliary subunits sometimes present as well [ 22 ] . An initial characterization of VR1 channels expressed in Cos and CHO cells has recently revealed that, under certain conditions, they run as multimers on pseudo-native (PFO) gels, with tetramers being one of the primary bands observed [ 23 ] . Thus, like other six membrane spanning domain channels, VR1 almost certainly forms as a tetramer; whether it combines with homologous subunits to form heteromeric channels remains to be determined.
To evaluate the full spectrum of T cells elicited in each patient by vaccination, we utilized tetramers made with the vaccine peptides (heteroclitic M26 and G209–2M) to isolate such cells.
The samples from these six patient had peptide-specific T cell populations detectable with G209–2M-tetramers (patients 422, 476, and 132) or M26-tetramers (patients 517, 520, and 461) ranging from 0.1% to 2.5% of total CD8+ T cells (Figure 1A).