Words similar to synuclein
Example sentences for: synuclein
How can you use “synuclein” in a sentence? Here are some example sentences to help you improve your vocabulary:
This is probably because ANOVA retains information about the experimental design; for the example of synuclein given in the results, it 'knows' that there is a large disagreement between two matched replicates in the midbrain samples, whereas the template match based on the correlation coefficient considers all variations to be essentially equivalent.
Mutations in α- synuclein include three point mutations (A30P, E46K, and A53T) and multiplication of the wild-type (normal) gene.
Presumably, neurons require α-synuclein for their normal function and thus cannot simply dispense with this protein that has toxic properties, although mice in which the α- synuclein gene is knocked out have no obvious deficits (see Dauer and Przedborski [2003] for discussion).
The phenotype of patients with α- synuclein mutations varies from PD to a more diffuse Lewy body disease in which pathology is detected in the cerebral cortex and other areas of the brain.
On the detrimental side of the cell survival equation is the PD gene that was discovered first, α -synuclein . The synaptic protein encoded by this gene, α-synuclein, is prone to aggregation, and, as is the case for other aggregating proteins, mutations in α- synuclein are associated with dominantly inherited disease.