Words similar to synthesis
Example sentences for: synthesis
How can you use “synthesis” in a sentence? Here are some example sentences to help you improve your vocabulary:
Moreover, despite multiple sites of action, the drug's actions cannot be dismissed as non-specific, because 4-AP had no effects on either 3β-hydroxysteroid dehydrogenase (3β-HSD)-mediated conversion of pregnenolone to progesterone, or androgen (androstenedione, 5αDHT)-stimulated progesterone synthesis.
The 26S proteasome is responsible for the bulk turnover of cytoplasmic and nuclear proteins in eukaryotic cells and also plays a key role in the regulation of cell cycle, signal transduction, transcription as well as antigen presentation [ 17 18 19 20 21 ] . Most of the known proteasomal substrates are marked and targeted to proteasome by ubiquitination [ 17 19 20 ] . Ubiquitination, however, is not an obligatory step for substrate targeting to proteasome [ 17 18 20 ] . The degradation of the ornithine decarboxylase (ODC), the rate-limiting enzyme for polyamine synthesis, involves a protein named antizyme (Az), which binds and targets ODC to 26S proteasome for degradation [ 18 ] . However, ODC has remained an "orphan" in Az-dependent proteasomal degradation.
The collection of results demonstrating that retinal is an excellent substrate for ALDH1A1 in vitro , that ALDH1A1 is responsible for the synthesis of retinoic acid in the cranial tissues of the mouse embryo, and that hematopoietic stem cells are characterized by high expression of ALDH1A1, have led to the hypothesis that the oxidation of retinal to retinoic acid is a key physiologic role for ALDH1A1 in hematopoietic stem cells.
Some of the proposed functions for p51 include: (i) stabilizing the t-RNA primer binding for the initiation of reverse transcription [ 11 ] , (ii) enhancement of strand displacement DNA synthesis [ 19 20 ] , and (iii) as a processivity factor in DNA synthesis [ 21 ] .
Isolation of total RNA and synthesis of cDNA were performed as previously described [ 19 ] . RT-PCR reactions of cDNAs were conducted in a total volume of 15 μl with 2 × Taqman Master Mix (Applied Biosystems) and primers at optimized concentrations.
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